Professor Joachim Messing
Rutgers researchers Joachim Messing, Rémy Bruggmann, and a team of international collaborators have described the genome of sorghum, a drought-tolerant African grass. The findings could one day help researchers to produce better food crops for arid regions with rapidly expanding human populations, such as West Africa, and new feedstocks for biofuel.
Research Associate Rémy Bruggmann

Messing, director of Rutgers’ Waksman Institute, has been deeply involved in both the rice genome and maize (corn) genome sequencing projects. In 1982, he developed the modified shotgun sequencing approach used in the sorghum sequencing that represents a significant advance in methodology.

This approach takes into account the highly repetitive nature of large genomes including many plant species and the human genome. By using paired sequence reads instead of single sequence reads, the scientists can jump over repeat sequences, constituting about 62 percent in sorghum, and produce an accurate and contiguous picture of the entire sorghum genome.

The investigators chose sorghum, which is in the same family (grasses) as maize, rice and wheat, because of its importance for civilization as food and animal feed, and more recently as the basis of a biofuel.

In the United States, sorghum is mainly used as feed and it is grown in the south because it

Bicolor Sorghum
tolerates drought. One variety, known as grain sorghum, is a food staple in places such as Africa and India. It is higher in protein and lower in fat content than maize and is close to maize in nutritional content. Its resistance to heat and water stress allow it to be grown in regions where corn or other grain crops cannot compete. 

Another variety – sweet sorghum – has a sweet stem and is thus similar to sugar cane. The Food and Agriculture Organization of the United Nations has introduced sweet sorghum in China because of the country’s interest in having a biofuel crop and its ability to grow in areas where corn would not. Brazil’s extensive biofuel economy is based on sugar cane and is regarded as the most productive biofuel crop in the world. Sweet sorghum rivals sugar cane for this application and sorghum is superior to corn as a biofuel since the entire plant may be used, not just the grain – the kernels of corn.

With an understanding of how properties of the grasses, such as drought resistance, sugar in the stem, or grain productivity are encrypted in their genes, researchers may be able to laterally move these genes around among these crop species to customize them based on the needs of geographic location and climate.

 

 

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